3/17/2023 0 Comments Tiled kitchensGet references, and check them before hiring anyone. You tend to get what you pay for with tile installation. Only if the person has extensive experience installing tile kitchen backsplashes. Is hiring a handyman for tile installation a good idea? These kitchen backsplash pricing Q&A covers important aspects of cost. Get estimates from multiple tile contractors that know they’re competing for the job. ![]() Choose ceramic tile (available in hundreds of great styles and colors) rather than an expensive material.Choose a simple design rather than something complex.There might be something there you fall in love with. Remove the old backsplash and dispose of it yourself.These tips will help you reduce your costs and get a backsplash you’ll be very pleased with. Saving Money on Kitchen Tile Backsplashes The service we offer uses only pre-screened tile contractors where you live, so you’ll receive competitive estimates from local experts. We suggest getting estimates from several tile contractors. The level of competition among tile pros where you live.Labor costs vary with handymen being the cheapest and tile contractors supplied by a general contractor being the most costly.The more complex the work is (outlets, windows, cabinets, creating a design), the higher the labor cost will be.Product line changes resulting in clearance and discount prices for some tile.The good/better/best grades for most materials.The reasons for the variance in both material and labor costs include: Table 1: Cost of Tile Backsplash: A Comparison at a Glance Type of Backsplashįactors Affecting the Cost of Tile Backsplashes The following table provides a quick overview of tile backsplash materials, installation and removal cost. Kitchen backsplash labor cost: $5 to $15 per square foot, more when a custom tile mosaic design is being created.Brick backsplash tile: $6-$18 per square foot.Stone backsplash tile: $10-$40 per square foot.Glass backsplash tile: $7-$25 per square foot.Porcelain backsplash tile: $4-$14 per square foot.Ceramic backsplash tile: $2-$12 per square foot.The price range takes into consideration a wide array of tile material. ![]()
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3/17/2023 0 Comments Roguelands cheats 9.2![]() v0.7.0.1 Fixed Lingering Caius Bug v0.9.1 Added Card. v0.6.7.1 Fixed Multiplayer Caius Watcherdemon Bugs. GitHub - SuperKael/Unofficial-Roguelands-Patch: The Unofficial Roguelands Patch fixes many of Roguelands bugs. These are listed on the Alchemy Station page. The Unofficial Roguelands Patch fixes many of Roguelands bugs. Although it is possible to dodge these attacks, it is still recommended that you bring a Combat Chip for Healing Ward, Bubble and/or Vitality as well as some healing items such as Elixir or Health Pack III's.However, since Caius is usually behind the wall, be wary so that you don't hit him. Explore procedurally generated Press J to jump to the feed. ![]() RogueLands is a 2D Multiplayer Post-Apocalyptic RPG with permanent death. This may not always work, as the shadow wall may reach up to the ceiling, in which case just find the gap and dash through it. 1.3k members in the RogueLands community. Once the shadow wall is moving towards you, jump a few times so you are over it, then repeatedly dash in the direction of the wall until you are over. Caius' Shadow Wall can also be dodged, but it requires quick hands.Caius aims where you are and around you, so making large movements is key here. Outlaw Rogue 2-Piece Your Mastery: Main Gauche has a 25 chance to fire a Pistol Shot. It is possible to dodge Caius' Shadow Swords by moving left and right to predict them. Outlaw Rogue Tier Set Bonuses in Patch 9.2.Get away from Caius to kill the slivers, as not to get overwhelmed.Droid: GOLD 15: - Type JKJKL at the TAB menu. He will stand still after summoning slivers. Roguelands Cheat Codes: - Submitted by: David K.He will suddenly lunge forward before creating the shadow wall Immediately go away from him.He will raise his hand before summoning shadow swords. 3/16/2023 0 Comments Tcl tk scrollableframe activetcl![]() wm_geometry ( "400x300+0+0" ) cf1 = CollapsibleFrame ( root, text = "Frame1", interior_padx = 6 ) cf1. open () if _name_ = "_main_" : try : from Tkinter import Tk, Button except ImportError : from tkinter import Tk, Button root = Tk () root. _is_opened = False def toggle ( self ): if self. _is_opened = True def close ( self ): self. pack ( expand = True, fill = X, padx = self. configure ( width = width ) def open ( self ): self. _interior_pady, ( list, tuple )): width += self. update () if width is None : width = self. _containerFrame, x = x, y = y, anchor = N + W, bordermode = "ignore" ) def _update_width ( self, width ): self. update () x = caption_separation + icon_x + width_of_icon y = - ( self. _update_width ( width )) def _place_caption ( self, caption_separation, icon_x, width_of_icon ): self. _place_caption ( caption_separation, icon_x, width_of_icon )) def update_width ( self, width = None ): # Update could be devil # self. _captionLabel, Widget ): raise Exception ( "'caption_builder' doesn't return a tkinter widget" ) self. _captionLabel = caption_builder ( self ) if not isinstance ( self. configure ( font = caption_font ) else : self. _captionLabel = Label ( self, anchor = W, borderwidth = 1, text = text ) if caption_font is not None : self. toggle ()) if caption_builder is None : self. _containerFrame, x = icon_x, y =- ( height_of_icon // 2 ), anchor = N + W, bordermode = "ignore" ) self. _collapseButton = Label ( self, borderwidth = 0, image = self. _containerFrame, background = background ) self. ![]() ![]() pack ( expand = True, fill = X, pady = ( containerFrame_pady, 0 )) self. _containerFrame = Frame ( self, borderwidth = borderwidth, width = width, height = height, relief = RIDGE, background = background ) self. width ()) containerFrame_pady = ( height_of_icon // 2 ) + 1 self. _iconClose = PhotoImage ( data = "R0lGODlhEAAQAKIAAP///9TQyICAgEBAQAAAAAAAAAAAAAAAACwAAAAAEAAQAAADMxi63BMgyinFAy0HC3XjmLeA4ngpRKoSZoeuDLmo38mwtVvKu93rIo5gSCwWB8ikcolMAAA7" ) height_of_icon = max ( self. _iconOpen = PhotoImage ( data = "R0lGODlhEAAQAKIAAP///9TQyICAgEBAQAAAAAAAAAAAAAAAACwAAAAAEAAQAAADNhi63BMgyinFAy0HC3Xj2EJoIEOM32WeaSeeqFK+say+2azUi+5ttx/QJeQIjshkcsBsOp/MBAA7" ) self. configure ( background = background ) self. _init_ ( self, master ) if background is None : background = self. # Author: Miguel Martinez Lopez # Version: 0.4 # Uncomment the next line to see my email # print("Author's email: %s"%"61706c69636163696f6e616d656469646140676d61696c2e636f6d".decode("hex")) try : from Tkinter import PhotoImage, Frame, Label, Widget from Tkconstants import * except ImportError : from tkinter import PhotoImage, Frame, Label, Widget from nstants import * class CollapsibleFrame ( Frame ): def _init_ ( self, master, text = None, borderwidth = 2, width = 0, height = 16, interior_padx = 0, interior_pady = 8, background = None, caption_separation = 4, caption_font = None, caption_builder = None, icon_x = 5 ): Frame. 3/16/2023 0 Comments Graphs about thebrain![]() Sebastian Seung at Princeton University, the original prophet of the connectome, the map captures a tiny chunk of the mouse’s visual cortex, less than 1,000 times smaller than a pea. In a stunning new brain map published in Cell, these cells are finally having their time in the spotlight. Without this long-forgotten half, the brain wouldn’t be the computing wizard we strive to imitate with machines. Previously considered “wallflowers,” these cells nurture neurons and fine-tune their connections, ultimately shaping the connectome. To connectomics, mapping the brain isn’t just an academic exercise to better understand ourselves-it could lead to more efficient AI that thinks like us.īut often ignored are the brain’s supporting characters: astrocytes-brain cells shaped like stars-and microglia, specialized immune cells. Nestled inside the brain’s wiring diagrams are the keys to consciousness, memories, and emotion. It’s easy to see why: as shockingly powerful mini-processors, neurons and their connections-together dubbed the connectome-hold the secret to highly efficient and flexible computation. Yet when it comes to brain mapping, they get all the limelight. (This is a problem with every other markdown editor.Neurons make up less than half of the brain. When typing bold or italic text, typing a space will no longer disable the formatting until another character is typed.Toolbar controls for applying superscript and subscript formatting.Underline and strike-through can now be applied freely, even in the middle of words.All new engine that makes application of formatting more consistent and predictable.Improved copy/paste that maintains the correct formatting of text even when the relevant markdown tags are not copied.Faster performance, especially with very long lines of text.Support for fixed page breaks (accessed through the insert menu).Improved toolbar including fast access to toggle markdown display and a new insert menu.Setting to disable email/phone number recognition.Toggle rendering of underscore tags as italics to match standard markdown.Reorganized notes editor preferences including new options:.Tables are now much more robust and can’t be accidentally broken by typing or deleting the wrong thing.Instantly create a table and specify its size with the new UI.You can even apply formatting to multiple cells at once. This includes applying formatting, justification, line styles, colors and more. Virtually everything that can be done in a document can now be done just as easily inside of a table. Formatting within tables is more powerful than ever.If normal content (not made of multiple cells) is copied and then multiple cells are selected prior to pasting, the content will be duplicated into every selected cell.You can even select a group of cells, copy it, then paste elsewhere in the document to create a new table.Cut, copy and paste can be used to move cells within a table or from one table to another.If an entire row or column is selected, it will be removed. Press the delete key to clear the cells.Once a group of cells has been selected, many features take advantage of this:.Move a cell or group of selected cells.The table theme editor where you can visually style a table with custom colors and themes.The table toolbar gives fast access to table-specific commands: ![]() Click the table toolbar button in the top left corner of a table to display the table toolbar.Set the width of a column simply by dragging the right edge.Insert a column or row anywhere by clicking the insert controls along the right and bottom sides.You can also drag these handles to move them or right click on a handle to open a context menu. Select a column or row using the column and row handles along the left and top sides.Select a group of cells by clicking and dragging or by holding shift and using the arrow keys.All new table controls for intuitive manipulation and editing.Tables are vastly improved with the ability to set column widths, customize colors, move cells, insert columns and rows, and much more. ![]() The second, according to the filename was intended for Theft, which seemed like it was going to be an Activity rather than a Diversion this time around before ultimately getting scrapped. The first was intended for the Taxi Activity, before it got downgraded to a Diversion. Unused icons intended for scrapped Activities. The regular Police Notoriety is used instead, no matter if any Ultor-related vehicles or Masako get destroyed. There's an unused Notoriety icon for the Ultor Corporation. Maybe Playa could originally recruit tag team members during the Activity?Īre there any remnants of the Ultor Notoriety in the final game? Purpose unknown.Ī Homie meant for the Demolition Derby Activity, called "ui_homie_misc_derby". It is, in fact used in the German and Japanese versions of the game as human shields aren't used there.Īn unused Homie referred to as "Bouncer". This was meant to be displayed on the map to show where stairs are, but the icon doesn't show up in the final.Īn unused icon of Jessica of The Brotherhood, probably intended for an earlier revision of the Bank Error In Your Favor mission. It also has a slightly updated icon in comparison to the previous entry. According to the bitmap files, it's out of position, being overlaid with the "9".Ī unused map icon for the train exists, suggesting that the form of transport was going to return. There is an unused grayed-out variant of the Racing Diversion, which is never used even if the player gets Gold. Strangely, no grayed-out variations of the icons exist implying that they didn't get far in development in comparison to the unused Taxi icon. Though those icons don't have names, they are related to the scrapped Guardian Angel and Hijacking Activities. It's also the only one to be referenced in the bitmap_sheets file. Map_start_taxi and map_start_taxi_grey seems to be for the Taxi Diversion, where it may have originally been an Activity during development. There are several unused icons that were intended for Activities or other elements. ![]() We beg your pardon - very bad things happen in this Sub-Page! 3/16/2023 0 Comments Bubble shooter download![]() Finally, classic bubble shooter often feature colorful and eye-catching graphics that make them visually appealing. In addition, bubble shooter games usually don't take a long time to finish, so they're perfect for players who want to play casual game. For one, this puzzle game is typically very easy to learn how to play, but there can be challenging levels that provide an enjoyable experience. There are many reasons why you will enjoy playing bubble shooter games. Finally, always keep an eye on the timer, pop bubbles, and finish the level before it runs out! Why play bubble shooter games? Secondly, use your power-ups wisely - save them for tougher levels or when you're struggling to make any progress. First, aim with your bubble cannon for the biggest clusters of colorful bubbles that you can and try to clear them all at once. Here are a few key things to remember when playing a bubble game in order to win more often. Bubble shooter game is easy to learn, hard to master, and always exciting. These are fast-paced, puzzle games where you shoot colorful bubbles into groups of three or more to remove them from the screen and bring down chains of same-coloured balls. If you’ve ever played a game like puzzle bobble, candy bubble, bubble shooter pro, you’ve played a bubble shooter game. You can also get bonus points by clearing board in as few shots as possible.Easy Best Free Bubble Shooter Games to Download and Play Azteca Bubbles You get more points for popping more in one shot. You can get them by popping certain combinations. Power-ups are special bubbles that can help you clear board faster. Once you pop, rest will shift down and you'll have a better chance at clearing board. Goal is to clear board by popping them all. Plan your shots ahead so you can make most of colors you have! You can see which color is next in line at bottom of screen. Once you pop enough, rest will clear out and you can move on to next level! Playing it is easy! Just aim your Bubble Shooter for free online at a cluster of same-colored and shoot. Download Arkadium's free, 4.5 star reviewed Bubble Shooter app from the app stores and take your fun on the run The History of Bubble Shooter The first recognized Bubble Shooter game was an arcade game released in Japan called Puzzle Bobble (in the US and other Western countries it was called Bust a Move). Game is also simple enough that Bubble Shooter play for free can be played for a few minutes at a time. Player can try to beat their own score or score of other players. It is a game that can be played over and over again. The goal is to clear the screen before the other player. In multiplayer mode, the player competes against another player. Download Bubble Shooter game can be played multiplayer. When played with multiple players, game is competitive and players can compare their scores. Game can be played in rounds, and gamer with most points at end of round wins. When playing with other players, goal is to score most points. The game is over when you reach the bottom of the screen. You can also make combos by popping multiple at the same time. When the gamer shoots, it pops and any that are touching it also pop. To play Bubble Shooter online player shoots at groups of two or more of the same color. When a group of three or more is made, pop and the player scores points. Goal of Bubble Shooter online for free is to make groups of three or more of same color. Bubble Shooter download for Windows 10/7 is easy to see and easy to play. It is set against a white background, it are brightly colored. There is no music, but there are sound effects when it are popped. Background in free Bubble Shooter game is white, it are different colors, including blue, green, pink, and yellow. Graphicsīubbles are large and easy to see. Bubble Shooter game for free can be played solo or with multiple players. Objective is to clear everything from screen by shooting them with the same color. It ends when player runs out or when all of it on screen has been popped. Objective is to score as many points as possible by shooting bubbles of same color into groups of three or more. Bubble Shooter is an online game that was released in 2000. 3/16/2023 0 Comments Notebooks pro webcam![]() Integrated microphone with RightSound™ technology: Enjoy crystal clear conversations, free from echo** and annoying background noise. RightLight™2 technology: Adjusts intelligently to produce the best possible images in dimly lighted or poorly backlighted settings. Higher megapixel performance: A true two-megapixel sensor. HD video: Video calling and sharing has never looked so real at 960 by 720 pixels. Premium autofocus: Your images stay razor-sharp, even in close-ups. Logitech’s glass lens designed in collaboration with Carl Zeiss®, the global leader in camera optics. Carl Zeiss® optics: Get more detail and clarity from Carl Zeiss® optics. Carl Zeiss® optics and autofocus keep images razor-sharp, even in extreme close-ups. The clip on the camera can be used with notebook panels up to 20mm thick and includes simple vertical tilt functionality.The official marketing text of Logitech QuickCam Pro for Notebooks webcam 2 MP as supplied by the manufacturerĮnjoy image-perfect detail and clarity on your notebook. The package comes with a carry case and a 12in desktop stand. While it worked reasonably well, it too, was not perfect and even when working well, we found it to be more distracting than it was useful. The software also allows for face tracking which attempts to keep your face in the centre of the frame at all times. These include a "do not disturb" shutter which replaces your image with an image of your choice and a number of image filters and silly add-ons like moustaches and whatnot which overlay on your face. In addition, there is also added functionality for video chat users which is compatible with a number of popular instant messaging applications such as Windows Live Messenger, Skype and Yahoo Messenger. The installation includes the QuickCam software which is an easy to use interface allowing you to tweak the image quality. An installation CD is provided with the unit which, once installed, is all you need to do. Setting up the QuickCam Pro is very simple. However, in the office environment it was exceptional, as a great deal of background chatter was eliminated. It does a good job of it too, but it is still not perfect. When employed, it attempts to clean the audio and remove any echo or background noise. Another proprietary technology used in this camera is RightSound. However, in our home environment, which has a PC with a beefy graphics card fan, the fan noise could still be heard. The integrated microphone was able to pick up voice with clarity and could cancel a good amount of excess noise. If you are planning to use this camera in a dim environment, we would recommend you use a desk lamp with a low watt bulb (preferably a 40W daylight balanced bulb) to add illumination to the subject being captured. It was on-par with most webcams we have reviewed and once an additional light source was added to the room, it was no longer a problem. The image wasn't unusable, it just wasn't particularly brilliant. However, in the dimly lit environment there was some noise in the image, even with the RightLight 2 technology in effect. The image was crisp with a high level of detail and no visual artefacts. ![]() In the outdoor environment, we had no major problems with the image quality. Images in the well lit environment looked crisp and clear but we found that when using RightLight 2, there tended to be some light blooming around the subject adding a slightly ethereal look. The camera uses a proprietary technology called RightLight 2 which automatically adjusts the image according to the lighting situation. On the whole, we were impressed with the results. We tested the camera in various environments including a well lit office environment, outdoors, and a dimly lit home environment. It captures excellent image quality in well lit areas and average images in dimly lit environments. The Logitech QuickCam Pro for Notebooks is a mid- to high-end webcam with a 2Mp sensor and an integrated microphone. 3/16/2023 0 Comments Mortgage calculator oregon![]() You should take into account loan limits on conventional loans set by FHFA.If you are refinancing your loan, you should treat the down payment amount as the equity you own in your home. The difference between home value and the mortgage amount is considered your down payment.Here are a few important points to help you understand the mortgage calculations: A table showing the difference in payments, total interest paid and amortization period under both schemes is also displayed. ![]() Many homeowners wish to accelerate their mortgage schedule through extra payments or accelerated bi-weekly payments. You are presented with a detailed mortgage payment schedule. It also calculates the sum total of all payments including one-time down payment, total PITI amount and total HOA fees during the entire amortization period. Borrowers who aren't exempt and have used a VA loan before are subject to a slightly higher VA funding fee.This free mortgage calculator helps you estimate your monthly payment with the principal and interest components, property taxes, PMI, homeowner’s insurance and HOA fees. VA buyers exempt from the VA funding fee include those with a disability rating greater than 10%, those who've received a Purple Heart and surviving spouses. VA specifics relate to the VA funding fee. While this calculator works for refinancing, we also have a specific VA refinance calculator for cash-out and IRRRLs here. Calculations for loan types differ due to the VA funding fee. VA loans provide both purchase and refinance options. Estimate your credit score for a more accurate VA loan payment. Interest rates typically vary based on several factors, including credit score. Loan term is the length you wish to borrow - typically 15 or 30 years. You can view current VA mortgage rates here. Interest rates in the calculator are for educational purposes only, and your interest rate may differ. Interest rates in the calculator include APR, which estimates closing costs and fees and is the actual cost of borrowing. The interest rate is the cost of borrowing. However, if you decide to put money down, it can reduce the VA funding fee - if required - and your overall monthly payment. VA loans do not require a down payment, and most VA borrowers choose $0 down. The down payment is an upfront amount paid towards the principal. Home value is the potential purchase price of the home, not including a down payment. In the "Advanced Settings" section, you can update the property taxes and insurance estimates for your specific location, though 1.2% and 0.35% are typical.Ī Look at the VA Loan Calculator's Inputs The calculator updates your estimated VA loan payment as you change the fields. To use the VA loan calculator, adjust the inputs to fit your unique homebuying or refinancing situation. ![]() Veterans United's VA loan calculator considers these factors and more to estimate your purchasing power with a VA loan more accurately. VA loans have unique factors that affect the accuracy of the payment, including the VA funding fee, VA disability rating, prior VA loan usage and the loan type. Broad Mortgage CalculatorĬalculating monthly payments for a VA loan is similar to other mortgage options, but it's not the same. VA loans have a variety of benefits, including the flagship benefits of $0 money down, no private mortgage insurance (PMI) and typically lower-than-average interest rates. VA loans are a government-backed mortgage program uniquely for Veterans, military members and select military spouses with a valid Certificate of Eligibility (COE). 3/16/2023 0 Comments Minecraft 1.5.2 hack![]() Because it gives you unlimited money/coins/gems/keys. Download Plants vs Zombies 2 Mod is the perfect choice for you, bringing many new discoveries for you when playing this version. With creating cute chibi for characters, rhythmic moving animations will surely conquer you no matter how difficult it is. The sound system is lively, creating dramatic and suspenseful battles between you/fruits and those obnoxious zombies. Owning a very beautiful interface with 3D graphics built with extremely invested shape. Merge Plants: Zombie Defense joins the dramatic riot of plants and zombies. It’s so wonderful, isn’t it? This shows that Hack Plants Vs Zombie 2 this version has been built with a lot of effort to bring eye-catching gameplay to everyone. You can go to ancient Egypt, the desert, the beach or the whole world in the distant future. Takes you to 11 different worlds, not just in the garden. Create many new feelings for you to play games less boring. In addition to the garden next to the boss’s house, now there are many other gardens with novel designs interwoven with the gloom of zombies. However, there has been a big change for players to experience the most interesting. Still building square gardens so you can grow plants. Zombies Heroes allows you to experiment with more classic characters. With zombies such as zombies wearing manhole covers, egypts, construction zombies, normal zombies, etc., each type has different skills to attack your flower army. Along with quizzes, the zombies also rank stupid to wise. Therefore, before using it, determine the specific purpose of the strategy. However, the quantity is limited, and to plant it, you also need the sun to grow it. However, after the zombies are stronger, you need improved and upgraded plants such as explosive plants, ice guns, fire plants, meat plants, and even bombs. With familiar plants such as Sunflower and Peashooter, Lava Guava and Laser Bean, Potatoes, peppers, beans, you will easily build yourself a satisfactory fighting squad in the early levels. In addition, ELECTRONIC ARTS promises in Plants vs Zombies 3 that there will be more updates and changes to have a new turning point for gamers. From there you will be able to build a specific battle formation to destroy those evil zombies. So understanding zombies and their allies are definitely something you need to learn when playing the game. In addition to being tough and strong, they are also wiser. However, you will also encounter terrible zombies. Passing the stage is still the publisher’s choice to challenge you, at each level you will meet more new fruit allies. Each mode will bring different game rules that will suit each person’s preferences. Plants vs Zombies 2 Mod has Adventure, Penny’s Pursuit, and Arena are the 4 official modes for gamers to experience. Refer to version 1 Plants vs Zombies with extremely attractive classic content. A level will also have many strategies to help you create arrangements to defeat zombies. Because zombies are constantly increasing with more powerful types and they are also smarter with each level you achieve. In favor of the creative element for gamers, it is necessary to build a strategy to create a strong fruit army. In particular, the game mode has many changes to create a game with more unique content. Divide specific areas such as farming, shopping, arena, or in-game currency. According to the illustrations, you will also clearly notice the more beautiful interface design, optimized for users to easily observe and interact in the game. 1 Download Plants vs Zombies 2 Mod – Fruit vs Zombie Warĭownload Plants vs Zombies 2 Mod – Fruit vs Zombie Warīelonging to the Casual game series, PvZ 2 was released by ELECTRONIC ARTS with enthusiastic investment. 3/16/2023 0 Comments Login sequence diagram![]() Secondary analysis support for Illumina’s TruSight Oncology 500 ctDNA. The DRAGEN Methylation Pipeline performs alignment, methyl calling, and calculates alignment and methylation metrics.Īccepts FASTA files, and builds the proprietary reference used by the DRAGEN apps.ĭRAGEN TruSight Oncology 500 ctDNA Analysis Software The DRAGEN Joint Genotyping/Population Pipeline calls variants jointly across multiple genomes and scales to large cohorts of samples at expedited speeds with uncompromising accuracy. The DRAGEN Single Cell RNA pipeline performs demultiplexing, cell-barcode and UMI error correction, sequence alignment, and quantification of gene expression. ![]() ![]() For differential expression, Illumina recommends the DRAGEN Differential Expression app on BaseSpace Sequence Hub. The DRAGEN RNA Pipeline performs transcriptome analysis starting with splice junction discovery and alignment, followed by rapid alignment and splice junction mapping and quantification. Includes a full suite of enrichment metrics and reporting. The DRAGEN Enrichment Pipeline combines DRAGEN’s germline and somatic callers into a pipeline designed specifically for analyzing enrichment samples. Both modes make no ploidy assumptions, enabling detection of low-frequency alleles. The DRAGEN Somatic Pipeline includes tumor-only and tumor–normal modes, designed for detecting somatic variants in tumor samples. The DRAGEN Germline Pipeline provides end-to-end NGS analysis, including advanced error model calibration for increased accuracy, and repeat expansion detection and genotyping through Illumina Expansion Hunter. These can help to predict how a system will behave and to discover responsibilities a class may need to have in the process. A sequence diagram is a good way to visualize and validate various runtime scenarios. The DRAGEN Map + Align can be run as a standalone or as part of DRAGEN’s suite of pipelines Sequence diagrams describe interactions among classes in terms of an exchange of messages over time. DRAGEN ORA compression is optimized for high compression ratios of FASTQ files, as well as rapid compression and decompression, all while preserving data integrity. |
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